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The number one bestselling textbook for the introductory biochemistry course because it brings clarity and coherence to an often unwieldy discipline, offering a thoroughly updated survey of biochemistry's enduring principles, definitive discoveries, and groundbreaking new advances with each edition.

This new Seventh Edition maintains the qualities that have distinguished the text since Albert Lehninger's original edition-clear writing, careful explanations of difficult concepts, helpful problem-solving support, and insightful communication of contemporary biochemistry's core ideas, new techniques, and pivotal discoveries. Again, David Nelson and Michael Cox introduce students to an extraordinary amount of exciting new findings without an overwhelming amount of extra discussion or detail. With this edition, W.H. Freeman and Sapling Learning have teamed up to provide the book's richest, most completely integrated text/media learning experience yet, through an extraordinary new online resource;



Chemical logic figures for each of the central metabolic pathways highlight the conservation of mechanism and illustrate patterns that make learning pathways easier.
Mechanism figures help students understand the reaction process step by step, explaining a consistent set of conventions for each mechanism.
Molecular structures created specifically for this book use consistent shapes and colour schemes.
In-text Worked Examples take students through particular difficult equations to improve their quantitative problem-solving skills.
More than 600 end-of-chapter problems give students further opportunity to practice what they have learned.



Chapter 1: The Foundations of Biochemistry
Chapter 2: Water
Chapter 3: Amino Acids, Peptides, and Proteins
Chapter 4: The Three-Dimensional Structure of Proteins
Chapter 5: Protein Function
Chapter 6: Enzymes
Chapter 7: Carbohydrates and Glycobiology
Chapter 8: Nucleotides and Nucleic Acids
Chapter 9: DNA-Based Information Technologies
Chapter 10: Lipids
Chapter 11: Biological Membranes and Transport
Chapter 12: Biosignaling
Chapter 13: Bioenergetics and Biochemical Reaction Types
Chapter 14: Glycolysis, Gluconeogenesis, and the Pentose Phosphate Pathway
Chapter 15: Principles of Metabolic Regulation
Chapter 16: The Citric Acid Cycle
Chapter 17: Fatty Acid Catabolism
Chapter 18: Amino Acid Oxidation and the Production of Urea
Chapter 19: Oxidative Phosphorylation and Photophosphorylation Oxidative Phosphorylation
Chapter 20: Carbohydrate Biosynthesis in Plants and Bacteria
Chapter 21: Lipid Biosynthesis
Chapter 22: Biosynthesis of Amino Acids, Nucleotides, and Related Molecules
Chapter 23: Hormonal Regulation and Integration of Mammalian Metabolism
Chapter 24: Genes and Chromosomes
Chapter 25: DNA Metabolism
Chapter 26: RNA Metabolism
Chapter 27: Protein Metabolism
Chapter 28: Regulation of Gene Expression.